Liquid medicine concocted at Byrgenwerth. Calms the nerves.

Those who delve into the arcane fall all-too-easily to madness, and thick human blood serves to calm the frayed nerves of these inquisitive minds. Naturally, this often leads to a reliance on blood ministration.

Sedative is a Consumable Item in Bloodborne.


Sedative Usage

  • Instantly clears frenzy status build-up and beasthood build-up.
  • Also removes the inability to use Healing Items brought on by the Moon Presence's Rain of Gore.





  • Sold by Messengers after gaining Cosmic Eye Watcher Badge from the Upper Cathedral Ward.
  • 8x Quest "reward" for sending the Lonely Old Woman to Oedon Chapel and talking to her multiple times after the sky turns night.
    • Answer "I have my woes" and she will give you 1, then 2, then 3. She will leave the chapel and when she comes back later will give you 1 more sedative. After giving you 7 sedatives she will again leave her seat. Her corpse can then be found outside with 1 last sedative, leaving the Oedon Chapel Dweller distraught and speculating what happened.
  • Drops from Slime Students in the Lecture Building.
  • Drops from Byrgenwerth flies.
  • 3x Drops from Rosmarinus wielding npc hunter in Nightmare of Mensis.
  • 5x Byrgenwerth, near the lake close to the shortcut gate.
  • 6x Lecture Building 2nd Floor, in the circular room across the hall from the Lamp.
  • 3x Nightmare of Mensis, on the spiral staircase inside Micolash boss arena, go down instead of up.



  • Notes go here



  • Trivia goes here



Antidote  ♦  Beast Blood Pellet  ♦  Blood of Adella  ♦  Blood of Arianna  ♦  Blood Vial  ♦  Blue Elixir  ♦  Bold Hunter's Mark  ♦  Bolt Paper  ♦  Bone Marrow Ash  ♦  Coldblood  ♦  Delayed Molotov  ♦  Delayed Rope Molotov  ♦  Fire Paper  ♦  Frenzied Coldblood  ♦  Gold Pendant  ♦  Great One's Wisdom  ♦  Great One Coldblood  ♦  Hand Lantern  ♦  Hunter's Mark  ♦  Iosefka's Blood Vial  ♦  Kin Coldblood  ♦  Lead Elixir  ♦  One Third of Umbilical Cord  ♦  Quicksilver Bullets  ♦  Red Jeweled Brooch  ♦  Shaman Bone Blade  ♦  Shining Coins  ♦  Tear Stone  ♦  Thick Coldblood  ♦  Tiny Music Box  ♦  Vermin

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