Brain of Mensis

Enemy Type Not Beast nor Kin
Health 9837
Drops Living String,  2181 Blood Echoes
Weak ??
Strong ??
Location Nightmare of Mensis

Brain of Mensis is an enemy in Bloodborne.

The Brain of Mensis , also known as "Mother Brain", is an enemy resembling a giant brain with various eyes and some beastly limbs. It is essentially a large version of Winter Lanterns, though without a body.

It is first encountered from a distant tower at the beginning of Nightmare of Mensis,  and will glow orange when the player is in line of sight, causing massive frenzy damage. This attack can hurt the player even from a very long distance, unless the environment is used to avoid its malignant gaze.

The Brain of Mensis  can be slain after defeating Micolash, Host of the Nightmare. The player can defeat it by using a lever in a side area, dropping the brain into a pit where it will be unable to attack the player further.



  • Have 10 Sedatives equipped. Awaken at the Mensis: Middle Loft lantern, and get into the bird cage elevator. During descent, there is a window you can jump into from the elevator.
  • Run across the bridge with the 3 Winter Lanterns, using the terrain and Sedatives to avoid Frenzy.
  • In the building, run past the Nightmare Apostles, descend the stairs, and pull the lever on the balcony, triggering a cut-scene that drops the Brain of Mensis  into a pit.
  • After the cut-scene, turn around and drop down into a hole on your right.
  • In the room, there are two spiders and a chest holding the Choir Bell item which is guarded by a Winter Lantern.
  • Run outside, jump down into the collapsed tower (avoiding the bottomless pit) and there is a body holding the Blood Rock.
  • Follow the path out onto the bridge and enter the building with Mergo's Attendants.
  • Go to the bottom floor with the holes in the ground, and ride the bird cage elevator located on the right side.
  • You will enter a pitch-black room where the Brain of Mensis  is now helpless and easy to kill.
  • IMPORTANT NOTE: Before attacking the brain, use the "Make Contact" gesture in front of it until your character's arms rotate, and you will receive the Tier 3 Moon Caryll Rune (Great One's Wisdom in NG+ if you already have it).



Attack Name Attack Description
Gaze If the player is within its line of sight, he/she will take continuous damage from this far-reaching attack.

NeoMerdien - video guide:

  • how to
  • how to


The Brain of Mensis Information

This enemy is unique as an important part of the story, and it is only found in one area in the game. There are no variants nor is it encountered in Chalice Dungeons.

living_string.png moon.jpg
Nightmare of Mensis 9387 2181 (1x) 100% (1x) 100%


Notes & Trivia

  • The Living String description states the Brain of Mensis is a Great One and was found in the Nightmare by Mensis.
  • The Brain of Mensis is the one attacking you with Frenzy as you try to make your way to the building and Mergo's Loft.
  • The location where the Brain of Mensis is dropped after you pull a lever in Nightmare of Mensis is completely pitch black on all of its surfaces, resembling the Abyss of Dark Souls.
  • It will not disappear from the game after you kill it, it will still drop blood echoes but no Living Strings (hence why the Nightmare of Mensis still remains).
  • You must use the "Make Contact" gesture in a very specific location, infront of the hand, in order to obtain the rune.
  • You can also do the "Make Contact" gesture after killing it (it doesn't have to be physically present) and still get the full Moon Caryll Rune.
  • There seems to be a bug where killing it with a cooperator can cause you to not receive the Living String.
  • The brain is often referred as "rotten" leaving us to believe that it may have corrupted the Dream of Mensis and made it the Nightmare of Mensis, as well as Micolash, who was the leader of the School of Mensis.


    • Anonymous

      16 Aug 2017 06:45  

      If anyone is wondering why you get frenzy, I assumed this game had heavy Lovecraftian influences. In the stories humans often went insane trying to comprehend otherworldly beings. I'm assuming Frenzy state and Madman knowledge is connected. Since the more Madman Knowledge you have in you inventory the more fatal frenzy will be to your health. As the more knowledge of the cosmic horror the more insane your mind is. It also explains why you start to see the old ones hanging in spots early on in the game the more knowledge you have.

      • Anonymous

        07 Jun 2017 16:10  

        I wonder if this thing is really TRYING to kill you with Frenzy, or if it's just calling out to you for some reason, maybe even for help. I get the feeling it doesn't really want to be strung up in that tower, plus it seems pretty chill when you make contact. Maybe... it's even trying to get you to kill it? It's also incredibly okay with you bashing its brains out (no pun intended).

        Also, those "beastly limbs" look a lot like withered versions of Amygdala's arms. The hands have six fingers, and there's a strange hole in the center of each palm. Though this detail is also seen in the scurrying creatures that carry the blood shards, which is kinda weird, so I'm not sure if this is directly relates the Brain to Amygdala or those hands are just a recurring detail.

        • Anonymous

          17 Apr 2017 01:33  

          Anyone looked real closely at the "body" of the brain. The parts which arent eyes/tentacles/hands appear to be made up of messengers.. Think on that

          • Anonymous

            30 Jan 2017 03:26  

            “This Cord granted Mensis audience with Mergo, but resulted in the stillbirth of their brains”…IMO, the mother brain is the stillbirth of Mensis's brains...

            • Anonymous

              30 Nov 2016 12:46  

              What I'm wondering is why doesn't the brain still try and frenzy and kill you once you're right up in its face?

              • Anonymous

                Mother brain05 Jul 2016 14:50  

                This is the enemy that is constantly frenzy you when you enter the area she shoots what seems to be endless amounts of spikes that cause frenzy buildup

                • Anonymous

                  Easter Egg or Refference05 Jul 2016 14:50  

                  Is it possible that mother brain is a Metroid reference dont realy know much about metroid but it seems that there also is an enemy called mother brain that looks a bit like this one

                  • Anonymous

                    thing made me scare05 Jul 2016 14:50  

                    I dropped it search the brain and saw the elevator used it searched everywhere to find a chest or so turned around and jumped in the eye i scared myself as hell

                    • Not spawning?05 Jul 2016 14:50  

                      Doesn't seem to wanna spawn for me. I tried reloading the save i tried going in and out but nothing. I even tried standing there for 10 minutes using the contact gesture. I killed all the bosses in the game exept gehrman. Help please!

                      • Anonymous

                        Kos/Kosm is not a great one, its Micolash having an incomplete thought.05 Jul 2016 14:50  

                        If you ever go and listen to the complete Micolash audio, you will note that he says "Kos, some say Kosm..." several times. Everybody who has not heard the entirety of the audio for Micolash will probably think "OH KOS IS A GREAT ONE." No, no he isn't. In the final audio clip of Micolash, he has a "revelation", realizing that Kos is really *The Cosmos*. Can not stress the Kos/Kosm misconception correction more. If you don't believe me, then please

                        • Anonymous

                          Contact05 Jul 2016 14:50  

                          Can confirm contact gesture gives you "Moon" rune when used in front of eye in dark depths below nightmare.

                          • Anonymous

                            "If you do the "Make Contact" gesture after killing it using the drop method (rather than fighting it directly) you can no longer get the rune."05 Jul 2016 14:50  

                            Can confirm this is FALSE. I just killed it by the drop method and did the gesture AFTER killing it. Still got the rune.

                            • Anonymous

                              Floating Window?05 Jul 2016 14:50  

                              Has anyone else seen the floating window thing above where Mother Brain is in the basement? looks kind of like a window or the side of a box or something.

                              • How to deal with The Brain05 Jul 2016 14:50  

                                Greetings Hunters!Created two vids showcasing how you can deal with The Brain on both instances and what you can get from it. Poisting the vids below, feel free to take a look if you are having problems. Enjoy!Part 1: 2:

                                • Anonymous

                                  Umbilical Cord05 Jul 2016 14:50  

                                  Based on the Third Umbilical Cord granted by Iosefka if you kill her, the description states: "Provost Willem sought the Cord in order to elevate his being and thoughts to those of a Great One, by lining his brain with eyes. The only choice, he knew, if man were to ever match Their greatness." Could this mean that Willem succeeded in becoming a Great One? His body is outside Rom's boss area, but it seems to be almost completely devoid of all intelligence or knowledge. His only action is pointing at the lake and mumbling, which is far from the cutscene after Vicar Amelia which depicted him as someone who was very intelligent, albeit a bit twisted in his ways according to Laurence. This is just a theory, but I think the 'Mother Brain' is actually Willem's brain, which ascended to the point where he became a Great One. We do know it's possible. The Cord says that he, like us, sought the umbilical cords, and lined his brain with eyes. The Mother Brain is lined with eyes, and we can ascend to being a Great One, if we get three of the Umbilical Cords.

                                  • Mother Brain before lever05 Jul 2016 14:50  

                                    I uploaded a video of Mother Brain before pulling the lever, just thought someone might want to see this:

                                    • Anonymous

                                      Now i know- Cosmos,Daughter of Cosmos-Space,Aliens are the source of all the blood healing05 Jul 2016 14:50  

                                      The wolves we're not the cause of the infection(the blood healing and blood healers) it was the aliens,the guys in the upper cathedral ward(I forgot what they're called) they were trying to cover the aliens AND the blood healing, Remember "When the red moon hangs low, the line between man and beast is blurred, and when The Great Ones descend, a womb will be blessed with child" yeah the woman who is pregnant(forgot her) u oughta slash her baby but not HER, coz she births an alien. Therefore It is revealed, also Gehrman/Gerhman(whatever) is the keeper of the hunter's dream therefore he is the.....($poiler Alert)

                                      • Anonymous

                                        Passive in The Abyss05 Jul 2016 14:50  

                                        Why is it that the brain does not turn hostile when dropped into the hole? Does the darkness have anything to do with it, and you simply cannot see it properly? Or is it that it is just injured from the fall?

                                        • I killed the brain and he came back afterwards?05 Jul 2016 14:50  

                                          So i didnt have the make contact gesture and didnt think i was going to find it, ended up killing the brain. Once i got the gesture, i learned he doesnt need to be there to get the ruin. When i came back he was all and well again being a brain? This happen to anyone else?

                                          • Anonymous

                                            you dont need any Sedatives05 Jul 2016 14:50  

                                            93 lvl, 30 vitality. Hat from Crowfeather Set +Ashen Hunter Set(higher frenzy res then Crow set items) without hat ofc. 171 frenzy res at all. Its enough to kill Frenzy Brains enemy before frenzy fully charged.Then frenzy takes your hp then 2 blood vial and you are full hp again

                                            • Anonymous

                                              "If you killed it by using the lever"05 Jul 2016 14:50  

                                              Is there a different way of killing it? That phrase makes it seem like you can access the brain without dropping it.

                                            Load more