Great Isz Chalice

great isz chalice.png

A chalice that breaks a labyrinth seal

Great chalices unlock deeper reaches of the labyrinth. The Great Isz Chalice became the cornerstone of the Choir, the elite delegation of the Healing Church

It was also the first Great Chalice brought back to the surface since the time of Byrgenwerth, and allowed the Choir to have audience with Ebrietas."

Great Isz Chalice is a Chalice Item in Bloodborne. You can create this chalice dungeon by combining the materials listed below at one of the Tomb Altars in Hunter's Dream. This dungeon never changes Bosses, design or loot.


Great Isz Chalice Information





  1. Brainsucker
  2. Celestial Emissary (with just himself)
  3. Ebrietas, Daughter of the Cosmos



  • An Illusionary Wall can be found in the 1st Layer. It's located in the pre-boss area inside a room housing a Keeper of the Old Lord enemy.



Sometimes, after you unlock the door to the next layer, the inhabitants of the dream (little ones) will capture you and throw you anywhere in the dungeon.



    • Anonymous

      20 Apr 2020 21:59  

      I'm so *****in confused. I've killed ebrietas, completed another ism chalice and the deepest I've gotten remains layer 3 heart. Am I missing something?

      • Anonymous

        05 Feb 2020 15:13  

        The treasure room on 3rd layer actually has 5 brainsucker so please don't charge in alone if you're not good summon Gremia or Wallar

        • Anonymous

          03 Feb 2020 15:25  

          The treasure room on 3rd layer( the one you have to climb a ladder and run through a bridge to open a door) has 3 brainsuckers(on each floor of the room one is on the right when you first enter), 2 werewolves on the top, 2 celestial mobs that use a call beyond(one is right in front of you so dodge/ run to the left and hide behind the collum when you enter) summon the old hunter to make it easier this room can kill you quickly if your vit is low. If you clear all the mobs here using moon runes 2&3 you can net 600k or more blood echoes.

          • Anonymous

            30 Jan 2020 07:54  

            The fake wall on 1st layer (in the room with the dogs) is on the left use the blue elixir and blood cocktail to avoid combat the fake wall is quite easy to recognize.

            • Anonymous

              30 Jan 2020 07:51  

              Good news if you only want platinum. You only need to kill 2 boss and clear out the first 2 layers(treasure room and all) to have enough blood ritual 5 ( there's a fake wall on 1st layer in the room with the keeper of the oldlord and hellhounds you can find 2 ritual blood) on the 3rd layer go to the room that has rolling rock and turn right run a little bit and turn left inside the room is a brainsucker and 3 chests. You can call the old hunter to make things a lot easier.

              • Anonymous

                07 May 2019 19:47  

                Maybe someone should add that info about the illusory wall to the corresponding section. So far it only mentions those in the Lower Pthumeru dungeon. And the messengers pulling you down and into a different room is a trap, marked by a circle of red candles.

                • Anonymous

                  17 Jan 2019 23:08  

                  if you're having trouble with him and you're using a skill build use 2 handed blade of mercy, target her head and smash R1 You're welcome

                  • Anonymous

                    25 Oct 2018 22:32  

                    Anyone still playing bloodborne and will continue to be for the next few months add me. My PSN is TvArtemisvT.

                    • Anonymous

                      19 Sep 2018 10:23  

                      when i saw it was layer 5 i thought it meant there were 5 bosses to contend with on 5 different levels. when fighting ebrietas we killed each other at the same time and upon my return i found no door to the next level down. i spent hours going round looking for another door or some way to progress. i lost several hundred thousand echoes to those damn pasta faced things and came to the conclusion it must only be a 3 layer at level 5. seems a great place to farm for levelling up though. that room on layer 3 with the little aliens and a couple of bad doggies gives nearly 80,000. not a bad return for a few minutes of hit and run.

                      • Anonymous

                        24 Aug 2017 16:11  

                        I got lost in the side area before Celestial Emissary while the Beckoner and another cooperator fought him... I was lost the entire time, I'm so embarrassed!

                        • Anonymous

                          14 Apr 2017 04:42  

                          Because finding the Red Jelly here is a pain in the ass:

                          Go to the rolling stone hallway
                          Follow the stones
                          Take a left
                          Beware the Brainsucker in the room
                          Loot chests for Red Jelly

                          • Anonymous

                            Trivia note isn't completely correct05 Jul 2016 14:35  

                            The same thing happens but sometimes it happens from just killing a standard enemy, happen when I killed a skeletal enemy on the first layer

                            • Anonymous

                              easy05 Jul 2016 14:35  

                              Its just too easy i think brainsucker 0 vials 0 bullets emessary 2 vials 0 bullets ebrietas 0 vials 0 bullets counting way to it and boss without leaving only used my lovely ludwig sword +10 at with that stats 50/40/50/30/30/40. Is it normal that this is the easiest depth 5 dungeon I played. Ihyll is the way harder so i think that ihyll is harder

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