Great Isz Chalice is a Chalice Item in Bloodborne. You can create this chalice dungeon by combining the materials listed below at one of the Tomb Altars in Hunter's Dream. This dungeon never changes Bosses, design or loot.

"A chalice that breaks a labyrinth seal.great isz chalice.png

Great chalices unlock deeper reaches of the labyrinth. The Great Isz Chalice became the cornerstone of the Choir, the elite delegation of the Healing Church

It was also the first Great Chalice brought back to the surface since the time of Byrgenwerth, and allowed the Choir to have audience with Ebrietas."

Great Isz Chalice Information



  1. Brainsucker
  2. Celestial Emissary (with just himself)
  3. Ebrietas, Daughter of the Cosmos


  • An Illusory Wall can be found in the 1st Layer. It's located in the pre-boss area inside a room housing a Keeper of the Old Lord enemy.


Sometimes, after you unlock the door to the next layer, the inhabitants of the dream (little ones) will capture you and throw you anywhere in the dungeon.

    • Trivia note isn't completely correct05 Jul 2016 08:35  

      The same thing happens but sometimes it happens from just killing a standard enemy, happen when I killed a skeletal enemy on the first layer

      • easy05 Jul 2016 08:35  

        Its just too easy i think <br/>brainsucker 0 vials 0 bullets <br/>emessary 2 vials 0 bullets <br/>ebrietas 0 vials 0 bullets <br/>counting way to it and boss without leaving only used my lovely ludwig sword +10 at with that stats <br/>50/40/50/30/30/40. Is it normal that this is the easiest depth 5 dungeon I played. Ihyll is the way harder so i think that ihyll is harder

        • Requesting help with Ebrietas.05 Jul 2016 08:35  

          My Ebrietas game is almost flawless. It's only the fact that she can one hit kill me her charge. I can dodge the charge but if I don't do it right even her arm will one hit kill me. I low leveled because I made this character to experience the dlc because what is the point of new areas if you're going to fly right through them? So I'm not leveling above level 60 right now. So if anyone feels like helping my psn is Ranger-935_ and the chalice glyph is j7frvz6. Conductor is Aemilia.

          • Boss05 Jul 2016 08:35  

            With the DLX you can ring two old hunter bells and just wreck her from behind while they take the aggro. Only think you have to watch out for is her flying backwards, if she hits ya you'll take dmg.

            • Is the brain sucker any good for farming flat arcane gems?05 Jul 2016 08:35  

              I've been farming the brain sucker about 3 times and have only gotten around arcane +30 and want radials and +60 or +70. Will he drop them?

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