Great Isz Chalice is a Chalice Item in Bloodborne. You can create this chalice dungeon by combining the materials listed below at one of the Tomb Altars in Hunter's Dream. This dungeon never changes Bosses, design or loot.
|"A chalice that breaks a labyrinth seal.
Great chalices unlock deeper reaches of the labyrinth. The Great Isz Chalice became the cornerstone of the Choir, the elite delegation of the Healing Church
It was also the first Great Chalice brought back to the surface since the time of Byrgenwerth, and allowed the Choir to have audience with Ebrietas."
- Drops from Ebrietas, Daughter of the Cosmos
- For higher chances of co-op with the Fextralife community, then join Fextra Isz dungeon via this Glyph: dezhu9v5
- An Illusory Wall can be found in the 1st Layer. It's located in the pre-boss area inside a room housing a Keeper of the Old Lord enemy.