Brain Fluid is a Key Item in Bloodborne.
brain_fluid.jpg "Greyish amoeba-shaped brain fluid. Wobbles and bounces.

Extracted from a patient whose head expanded until that was all that they were.

In the early days of the Healing Church, the Great Ones were linked to the ocean, and so the cerebral patients would imbibe water, and listen for the howl of the sea. Brain fluid writhed inside the head, the initial makings of internal eyes.

Once, a young girl had an older brother who was determined to become a doctor, and so she wilfully became his patient. In the end, this led to their encounter with the Eldritch Truth, for which they considered themselves blessed.

We fail to realize our own latent potential, until the moment it is lost, and we sense its absence. Ironically, this is the very nature of insight, like the moment one licks one's own blood, only to be startled by its sweetness."

Brain Fluid Usage

  • Brain Fluid is given to Saint Adeline to progress an in-game quest to receive the Milkweed Caryll Rune. There are 3 places to find it.


  • Drops off the enlarged head at the highest point of the research hall on the uppermost catwalk in the corner across a crow. This is accessed after turning the main tower in the Research Hall. (Can be reached early by dropping to another platform close to where you reached the top level and climbing up another ladder)
  • Drops off the enlarged head on the middle platform that is guarded by a hunter and minigun user in a wheelchair.
  • Drops off of Saint Adeline after she has turned into an enlarged head without a body. She comes back to life after killing her for the fluid.
  • This item can only be gotten once per enlarged head (including Adeline).
  • Hostile enlarged heads do not drop this.


  • Player note 1


Trivia goes here

*Note* Saint Adeline must be given the first 2 Brain Fluids before she will turn into a enlarged head herself. Returning to the Hunters Dream multiple times seems adequate to move her in between in between states which will cause her to ask for more Brain Fluid.

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    • 10 Aug 2020 15:58  

      you'll know when it's time to kill Adeline because she'll have escaped the chair and she'll be in the corner of the room next to the door. her death is awful :(

      • Anonymous

        10 May 2020 09:44  

        Whoever made this page and didn't mention that you need to warp out before killing her deserves to get shot in the face

        • Anonymous

          21 Mar 2020 15:46  

          Dont kill her after giving the two brain fluids! Keep reloading the area until her head is HUGE, otherwise she'll still be mortal and die permanently like she did for me

          • Anonymous

            12 Jan 2020 16:51  

            Oh one drops off Adeline and she respawns after thats cool, accept not when you forget to mention thats after giving her the first two and leading people to kill her early wherein she doesn’t respawn. Change the headass retard description.

            • Anonymous

              22 Jan 2017 22:34  

              "The cerebral patients would imbibe water, and listen for the howl of the sea."

              I wonder if this has to do with hyperhydration, or "water intoxication." When a person drinks too much water, their cells often become oversaturated, especially in the brain. This causes severe headaches, as well as delusions.

              It seems also to tie in with the medical condition, hydrocephalus, in which an excess of spinal fluid and/or water in the brain causes a child's head to enlarge. In some cases, the skull becomes incapable of encasing the brain.

              Which begs the question... Is there a possibility that "paleblood" is nothing more than water? Or at least, is paleblood simply the plasma within our blood, devoid of its cellular and genetic content? After all, much of the arcane attacks in the game are represented by either water or ice, and there's the obvious correlation to the "Bulwark Sea..."

              • Anonymous

                Brain fluid missed04 Aug 2016 23:22  

                Hi there, Somehow I forgat to take which fluid guarded by hunter and then I opened living failures boss. Finally simon appeared. Is there any possible way to take it ??

                • Anonymous

                  item description05 Jul 2016 14:33  

                  Each Brain Fluid has its unique description. The one listed us the description for the final one (from Adeline).

                  • Anonymous

                    Darkbeast park isn't required05 Jul 2016 14:33  

                    The badge is in a room to the right where the chandelier falls go right of the staircase and go into a hallway where a brainsucker is and the corpse should be in that hallway

                    • Anonymous

                      Heres a Tip05 Jul 2016 14:33  

                      the A.I is still dumb so make the hunter follow you up to the top of the stairs with no handlebars then either make him dash off or push him off with the combat axe

                      • Anonymous

                        help!05 Jul 2016 14:33  

                        I can't kill one of them. It just keeps on reviving immediately after I kill it and I can't get the fluid

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